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He hasn't had as much math as, say Lichtmann, but James' feel for experimental design and control is much, much better than almost all of his competition's.
James doesn't load his studies with R^2 values, but James' studies -- and he has done hundreds of studies that would have received A's on masters' dissertations -- isolate variables correctly. James, not his competition, logically deduces which moving parts have not been captured within a given system. Which is why he's always ahead of where the BP and Fangraphs folks are.
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Agree that James, like Einstein, is a relatively self-taught genius with gaps in his education. Great point. I wish this didn't cause people to assume that he's ignorant of experimental design and control.