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If Paxton is a 130/150/170/200 inning guy (take your pick), innings are still innings.
If he's on a 130 inning limit in Seattle he would still be on a 130 inning limit in Tacoma.
Ergo: an innings limit is NO argument for not putting him in an M's uniform, if he's got the talent to wear it.
By the way, your point about a game PITCH limit and radar gun watchfullness is right on. Wasn't it Nolan Ryan who lamented about the fact that pitchers don't throw enough when young?