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Someday I'll launch my crusade against trying to evaluate baseball by putting all of everything into one number.
I always evaluate ISO-against for pitchers in combination with things like K/9, BB/9, WHIP, HR%, XBH%, etc.
The more colored boxes the better!
Sure, the difference between .120 and .140 probably is without substance. The difference between .120 and .050 probably is.
In other words, I tend to zero in on it when it is really low.